Visualization of tumor vessels using synchrotron radiation-based micro computed tomography

Three-dimensional characterization of cell clusters using synchrotron-radiation-based micro-computed tomography.

Micro-computed tomography with the highly intense, monochromatic X rays produced by the synchrotron is a superior method to nondestructively measure the local absorption in three-dimensional space. Because biological tissues and cells consist mainly of water as the surrounding medium, higher absorbing agents have to be incorporated into the structures of interest. Even without X-ray optics such...

Three-Dimensional Imaging of Hepatic Sinusoids in Mice Using Synchrotron Radiation Micro-Computed Tomography

Hepatic sinusoid, the smallest vessel in the liver, plays important roles in hepatic microcirculation. Although the structure of the hepatic sinusoids affects diverse functions of the liver, little is known about morphological alterations in the sinusoids under pathological conditions. In this study, we show that the structure of hepatic sinusoids can be identified three-dimensionally in normal...

Automated segmentation of synchrotron radiation micro-computed tomography biomedical images using Graph Cuts and neural networks

Synchrotron Radiation (SR) X-ray micro-Computed Tomography (mCT) enables magnified images to be used as a non-invasive and non-destructive technique with a high space resolution for the qualitative and quantitative analyses of biomedical samples. The research on applications of segmentation algorithms to SR-mCT is an open problem, due to the interesting and well-known characteristics of SR imag...

Observation of embolism formation and spreading in plants using synchrotron based X-ray micro computed tomography

Visualization of simulated small vessels on computed tomography using a model-based iterative reconstruction technique

This article describes a quantitative evaluation of visualizing small vessels using several image reconstruction methods in computed tomography. Simulated vessels with diameters of 1-6 mm made by 3D printer was scanned using 320-row detector computed tomography (CT). Hybrid iterative reconstruction (hybrid IR) and model-based iterative reconstruction (MBIR) were performed for the image reconstr...